Menarini Biomarkers Singapore – Single cells resolution for precision diagnostics

Isolation of single circulating trophoblasts from maternal circulation for noninvasive fetal copy number variant profiling.
Prenatal diagnosis, Doffini et al
– DOI (10.1002/pd.6275)

A first clinical study enrolling 372 pregnant women has been completed, showing 100% concordance of our genetic analysis on circulating trophoblasts with the data generated by standard of care prenatal diagnosis.

A second clinical study enrolling 2000 pregnant women is in progress. In this study we are comparing microarray data obtained by standard of care prenatal diagnosis with data generated on the same patients with our CB-NIPT test.