Ferrofluid CELL SEARCH
Ferrofluid-based capture reagent is the upstream technology to enrich and capture target cells from liquid biopsies. The ferrofluid reagent consists of particles with a magnetic core surrounded by a polymeric layer coated with antibodies. For example, anti-EpCAM antibodies conjugated with ferrofluid reagent, have been used to enrich and capture CTCs of epithelial origin, using the CELLSEARCH® system. Any antibody can be conjugated to ferrofluid reagent for immunomagnetic capture and enrichment of specific target cells of interest.